Pathology: Solid Tumor Core

Overview of Services

The main objective of the Pathology Core, supported by the National Cancer Institute-funded Cancer Center Support Grant, is to provide access to optimally preserved tumors and normal tissues to City of Hope researchers. Several thousand samples of diverse neoplasms are currently available in the frozen tumor bank. Additionally, many samples of normal tissue are available. Periodic inventories and sample testing are conducted to ensure quality of morphologic preservation and DNA/RNA integrity. All entries are recorded in a computerized database, and complete follow-up information is available for most samples in the tumor bank.

Optimally fixed samples of each tumor, often in more than one type of fixative, are available. In addition, multitissue blocks, containing many types of tumor and normal tissue, are available to facilitate retrospective screenings of new antibodies by immunohistochemistry and new molecular probes by in situ hybridization methods. Additional assistance and training in the performance of these techniques are provided to researchers for a nominal fee. Consultations with the users of this core facility by a qualified pathologist and/or molecular biologist are required.

 

Scheduling Services
Researchers wishing to utilize Pathology Core services must register each project by following these procedures:

 

  • Fill out a Tumor Bank Registration Form for each project. This is required by the National Institutes of Health and must be kept on file with the Pathology Core.
  • Submit a brief description of the project with tissue requirements and copy of IRB approval to Peiguo Chu, M.D., Ph.D., director of Surgical Pathology.
  • Obtain approval from the Department of Pathology for all requests using patient clinical material (fresh tissue from the gross room, slides and blocks).
  • Discuss the project with a staff pathologist to determine the type and amount of tissue needed and whether paraffin sections, clinical information from the surgical pathology report, etc. are also needed. We prefer to gather all the material together at one time in the interest of efficiency. Costs can also be discussed at this time.

Research reported in this publication included work performed in the Pathology Core supported by the National Cancer Institute of the National Institutes of Health under award number P30CA33572. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health 

Leadership Personnel  

Peiguo Chu, M.D., Ph.D.
Director 
X 62456
pchu@coh.org

 

Karen Miller, CLS, MT(ASCP)
Sr. Manager, Pathlogy Cores & Biobanking
X 88419
kamiller@coh.org

Olga Danilova, MD
Faculty Lead

odanilova@coh.org

Leanne Goldstein
Contact for assistance with study cohort
X 32002
RI_HELP@coh.org


Susan Murphy
Contact for protocol review committee (CPRMC)

X 62538
smurphy@coh.org

IRB
Contact for protocol review committee (IRB)

X 62700
irbsubmit@coh.org

Bridget Flanagan
Contact for assistance with new study application in iRIS (medical center)

X 63325
bflanagan@coh.org

Caroline Song
Contact for assistance with new study application in iRIS (Beckman research)

X 65769
csong@coh.org

Alysha Baker
Histotechnologist II

abaker@coh.org

Amberlynn Bird
Histotechnologist

abird@coh.org

Location and hours of operation

Hours Location

7:30am to 6:30pm      

Familian Science,1500 E Duarte Rd, Duarte, CA 91010   

Links and Resources

  1.  For Molecular Pathology Services please contact the Translational Research Laboratory
  2. http://www.coh.org/shared-resources/pathology/Pages/default.aspx
  3. http://www.coh.org/shared-resources/pathology/Documents/LOI%20for%20New%20study%20application.pdf
  4. http://www.coh.org/shared-resources/pathology/Documents/LOI%20for%20existing%20application.pdf

Contacts

Name Role Phone Email Location
Peiguo Chu, M.D., Ph.D.
Director
 
X 62456
 
pchu@coh.org
 

 
Karen Miller
Sr. Manager, Pathlogy Cores & Biobanking
 
X 88419
 
kamiller@coh.org
 
Familian Sciences Bldg. (#84), Lower level-L001C
 
Olga Danilova, M.D.
Faculty Lead
 

 
odanilova@coh.org
 

 
Alysha Baker
Histotechnologist II
 

 
abaker@coh.org
 

 
Amberlynn Bird
Histotechnologist
 

 
abird@coh.org